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1.
Rev Sci Instrum ; 93(1): 013306, 2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-35104937

RESUMO

A challenge preventing successful inverse kinematics measurements with heavy nuclei that are not fully stripped is identifying and tagging the beam particles. For this purpose, the HEavy ISotope Tagger (HEIST) has been developed. HEIST utilizes two micro-channel plate timing detectors to measure the time-of-flight, a multi-sampling ion chamber to measure energy loss, and a high-purity germanium detector to identify isomer decays and calibrate the isotope identification system. HEIST has successfully identified 198Pb and other nearby nuclei at energies of about 75 MeV/A. In the experiment discussed, a typical cut containing 89% of all 198Pb80+ in the beam had a purity of 86%. We examine the issues of charge state contamination. The observed charge state populations of these ions are presented and, using an adjusted beam energy, are well described by the charge state model GLOBAL.

2.
Phys Rev Lett ; 126(15): 152701, 2021 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-33929230

RESUMO

The discrepancy between observations from γ-ray astronomy of the ^{60}Fe/^{26}Al γ-ray flux ratio and recent calculations is an unresolved puzzle in nuclear astrophysics. The stellar ß-decay rate of ^{59}Fe is one of the major nuclear uncertainties impeding us from a precise prediction. The important Gamow-Teller strengths from the low-lying states in ^{59}Fe to the ^{59}Co ground state are measured for the first time using the exclusive measurement of the ^{59}Co(t,^{3}He+γ)^{59}Fe charge-exchange reaction. The new stellar decay rate of ^{59}Fe is a factor of 3.5±1.1 larger than the currently adopted rate at T=1.2 GK. Stellar evolution calculations show that the ^{60}Fe production yield of an 18 solar mass star is decreased significantly by 40% when using the new rate. Our result eliminates one of the major nuclear uncertainties in the predicted yield of ^{60}Fe and alleviates the existing discrepancy of the ^{60}Fe/^{26}Al ratio.

3.
Phys Rev Lett ; 118(5): 052501, 2017 Feb 03.
Artigo em Inglês | MEDLINE | ID: mdl-28211717

RESUMO

Previous experiments observed a 4^{+} state in the N=28 nucleus ^{44}S and suggested that this state may exhibit a hindered E2-decay rate, inconsistent with being a member of the collective ground state band. We populate this state via two-proton knockout from a beam of exotic ^{46}Ar projectiles and measure its lifetime using the recoil distance method with the GRETINA γ-ray spectrometer. The result, 76(14)_{stat}(20)_{syst} ps, implies a hindered transition of B(E2;4^{+}→2_{1}^{+})=0.61(19) single-particle or Weisskopf units strength and supports the interpretation of the 4^{+} state as a K=4 isomer, the first example of a high-K isomer in a nucleus of such low mass.

4.
Bone ; 78: 174-85, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25896952

RESUMO

PURPOSE: Adherence and persistence with bisphosphonates are frequently poor, and stopping, restarting, or switching bisphosphonates is common. We evaluated bisphosphonate change behaviors (switching, discontinuing, or reinitiating) over time, as well as fractures and costs, among a large, national cohort of postmenopausal veterans. METHODS: Female veterans aged 50+ treated with bisphosphonates during 2003-2011 were identified in Veterans Health Administration (VHA) datasets. Bisphosphonate change behaviors were characterized using pharmacy refill records. Patients' baseline disease severity was characterized based on age, T-score, and prior fracture. Cox Proportional Hazard analysis was used to evaluate characteristics associated with discontinuation and the relationship between change behaviors and fracture outcomes. Generalized estimating equations were used to evaluate the relationship between change behaviors and cost outcomes. RESULTS: A total of 35,650 patients met eligibility criteria. Over 6800 patients (19.1%) were non-switchers. The remaining patients were in the change cohort; at least half displayed more than one change behavior over time. A strong, significant predictor of discontinuation was ≥5 healthcare visits in the prior year (11-23% more likely to discontinue), and discontinuation risk decreased with increasing age. No change behaviors were associated with increased fracture risk. Total costs were significantly higher in patients with change behaviors (4.7-19.7% higher). Change-behavior patients mostly had significantly lower osteoporosis-related costs than non-switchers (22%-118% lower). CONCLUSIONS: Most bisphosphonate patients discontinue treatment at some point, which did not significantly increase the risk of fracture in this majority non-high risk population. Bisphosphonate change behaviors were associated with significantly lower osteoporosis costs, but significantly higher total costs.


Assuntos
Difosfonatos/uso terapêutico , Osteoporose Pós-Menopausa/tratamento farmacológico , Idoso , Idoso de 80 Anos ou mais , Índice de Massa Corporal , Conservadores da Densidade Óssea/uso terapêutico , Estudos de Coortes , Feminino , Hospitais de Veteranos , Humanos , Adesão à Medicação , Pessoa de Meia-Idade , Processamento de Linguagem Natural , Fraturas por Osteoporose/tratamento farmacológico , Fraturas por Osteoporose/prevenção & controle , Avaliação de Resultados da Assistência ao Paciente , Modelos de Riscos Proporcionais , Estados Unidos , Veteranos
5.
Phys Rev Lett ; 106(2): 022502, 2011 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-21405225

RESUMO

The transition rates for the 2(1)+ states in (62,64,66)Fe were studied using the recoil distance Doppler-shift technique applied to projectile Coulomb excitation reactions. The deduced E2 strengths illustrate the enhanced collectivity of the neutron-rich Fe isotopes up to N = 40. The results are interpreted using the generalized concept of valence proton symmetry which describes the evolution of nuclear structure around N = 40 as governed by the number of valence protons with respect to Z ≈ 30. The trend of collectivity suggested by the experimental data is described by state-of-the-art shell-model calculations with a new effective interaction developed for the fpgd valence space.

6.
Phys Rev Lett ; 102(14): 142501, 2009 Apr 10.
Artigo em Inglês | MEDLINE | ID: mdl-19392430

RESUMO

The results of measurements of the production of neutron-rich nuclei by the fragmentation of a 76Ge beam are presented. The cross sections were measured for a large range of nuclei including 15 new isotopes that are the most neutron-rich nuclides of the elements chlorine to manganese (50Cl, 53Ar, ;{55,56}K, ;{57,58}Ca, ;{59,60,61}Sc, ;{62,63}Ti, ;{65,66}V, 68Cr, 70Mn). The enhanced cross sections of several new nuclei relative to a simple thermal evaporation framework, previously shown to describe similar production cross sections, indicates that nuclei in the region around 62Ti might be more stable than predicted by current mass models and could be an indication of a new island of inversion similar to that centered on 31Na.

7.
Phys Rev Lett ; 101(25): 252501, 2008 Dec 19.
Artigo em Inglês | MEDLINE | ID: mdl-19113700

RESUMO

The beta-decay properties of the N=Z nuclei 96Cd, 98In, and 100Sn have been studied. These nuclei were produced at the National Superconducting Cyclotron Laboratory by fragmenting a 120 MeV/nucleon 112Sn primary beam on a Be target. The resulting radioactive beam was filtered in the A1900 and the newly commissioned Radio Frequency Fragment Separator to achieve a purity level suitable for decay studies. The observed production cross sections of these nuclei are lower than predicted by factors of 10-30. The half-life of 96Cd, which was the last experimentally unknown waiting point half-life of the astrophysical rp process, is 1.03_{-0.21};{+0.24} s. The implications of the experimental T_{1/2} value of 96Cd on the abundances predicted by rp process calculations and the origin of A=96 isobars such as 96Ru are explored.

8.
Nature ; 449(7165): 1022-4, 2007 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-17960237

RESUMO

A fundamental question in nuclear physics is what combinations of neutrons and protons can make up a nucleus. Many hundreds of exotic neutron-rich isotopes have never been observed; the limit of how many neutrons a given number of protons can bind is unknown for all but the lightest elements, owing to the delicate interplay between single particle and collective quantum effects in the nucleus. This limit, known as the neutron drip line, provides a benchmark for models of the atomic nucleus. Here we report a significant advance in the determination of this limit: the discovery of two new neutron-rich isotopes--40Mg and 42Al--that are predicted to be drip-line nuclei. In the past, several attempts to observe 40Mg were unsuccessful; moreover, the observation of 42Al provides an experimental indication that the neutron drip line may be located further towards heavier isotopes in this mass region than is currently believed. In stable nuclei, attractive pairing forces enhance the stability of isotopes with even numbers of protons and neutrons. In contrast, the present work shows that nuclei at the drip line gain stability from an unpaired proton, which narrows the shell gaps and provides the opportunity to bind many more neutrons.

9.
Phys Rev Lett ; 99(4): 042503, 2007 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-17678356

RESUMO

Transition rate measurements are reported for the 2(1)+ and 2(2)+ states in N=Z 64Ge. The experimental results are in excellent agreement with large-scale shell-model calculations applying the recently developed GXPF1A interactions. The measurement was done using the recoil distance method (RDM) and a unique combination of state-of-the-art instruments at the National Superconducting Cyclotron Laboratory (NSCL). States of interest were populated via an intermediate-energy single-neutron knockout reaction. RDM studies of knockout and fragmentation reaction products hold the promise of reaching far from stability and providing lifetime information for excited states in a wide range of nuclei.

10.
Phys Rev Lett ; 99(19): 192501, 2007 Nov 09.
Artigo em Inglês | MEDLINE | ID: mdl-18233071

RESUMO

The decay of extremely neutron-deficient 45Fe has been studied in detail by means of a novel type of a gaseous detector employing digital imaging to record tracks of charged particles. The two-proton radioactivity channel was clearly identified. For the first time, the angular and energy correlations between two protons emitted from the nuclear ground state were determined, indicating the genuine three-body character of this decay. The half-life of 45Fe was found to be 2.6+/-0.2 ms and the observed 2p decay branching ratio is 70+/-4%.

11.
Nature ; 418(6900): 859-62, 2002 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-12192405

RESUMO

The periodic table provides a classification of the chemical properties of the elements. But for the heaviest elements, the transactinides, this role of the periodic table reaches its limits because increasingly strong relativistic effects on the valence electron shells can induce deviations from known trends in chemical properties. In the case of the first two transactinides, elements 104 and 105, relativistic effects do indeed influence their chemical properties, whereas elements 106 and 107 both behave as expected from their position within the periodic table. Here we report the chemical separation and characterization of only seven detected atoms of element 108 (hassium, Hs), which were generated as isotopes (269)Hs (refs 8, 9) and (270)Hs (ref. 10) in the fusion reaction between (26)Mg and (248)Cm. The hassium atoms are immediately oxidized to a highly volatile oxide, presumably HsO(4), for which we determine an enthalpy of adsorption on our detector surface that is comparable to the adsorption enthalpy determined under identical conditions for the osmium oxide OsO(4). These results provide evidence that the chemical properties of hassium and its lighter homologue osmium are similar, thus confirming that hassium exhibits properties as expected from its position in group 8 of the periodic table.

12.
J Am Soc Echocardiogr ; 10(1): 60-6, 1997.
Artigo em Inglês | MEDLINE | ID: mdl-9046494

RESUMO

The purpose of this study was to determine, in an adult population, the percentage of patients in whom high quality pulmonary venous flow velocity recordings can be obtained using current transthoracic pulsed wave Doppler techniques. Pulmonary venous and mitral flow velocity variables obtained with a pulsed wave Doppler method were used for the indirect assessment of left ventricular (LV) diastolic function and LV filling pressures. The general clinical use of these methods, however, remains uncertain because the transthoracic success rate of obtaining all components of pulmonary venous flow velocity has been variable, and sometimes reported to be as low as 30% to 60%. Mitral and pulmonary venous flow velocity variables were obtained using pulsed wave Doppler signals in 200 consecutive adult patients (mean age 68.2 +/- 11.4 years) in normal sinus rhythm who were referred for echocardiographic study. Six cardiac sonographers and five ultrasound systems were used. The success rate for obtaining pulmonary venous systolic and diastolic flow velocity was 95%, reverse flow velocity at atrial contraction was 90%, and the duration of reverse flow at atrial contraction was 89%. In the 5% to 11% of patients in whom pulmonary flow velocities could not be adequately recorded, the most common reasons were depth limitations of the pulsed wave Doppler machine, marked cardiac enlargement, or left atrial wall motion artifact. The success rate also was influenced by the ultrasound equipment used, individual variation among sonographers, and even the type (impaired, pseudonormal, restricted) of associated mitral filling pattern. Given current machine technology, sonographer education, and daily practice, high quality, complete recordings of pulmonary venous flow velocity can be obtained in approximately 90% of adult patients using the precordial transthoracic Doppler technique. These results suggest that using these variables as an aid for evaluating LV diastolic function and filling pressures may have broader clinical applicability than previously appreciated.


Assuntos
Velocidade do Fluxo Sanguíneo , Ecocardiografia Doppler , Veias Pulmonares/fisiopatologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Átrios do Coração/fisiopatologia , Cardiopatias/diagnóstico por imagem , Cardiopatias/fisiopatologia , Humanos , Masculino , Pessoa de Meia-Idade , Valva Mitral/fisiopatologia , Contração Miocárdica , Função Ventricular Esquerda
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